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Formulation and Evaluation of Telmisartan Sustained-Release Tablets
(Book Rivers, 2026) Suraj Kumar, Mohd Arsh Khan, Sabahat Yasmeen Sheikh, Firoz Hassan
The study concentrates on developing and accessing extended-release floating tablets that include Telmisartan, a medication typically prescribed for treating hypertension. Different polymer ratios were utilized in creating various formulations through direct compression methods to regulate the release of the drug. Quality assurance measures encompassed testing pre-compression and post-compression parameters such as hardness, friability, and drug content. One of the formulations, F5, stood out for its optimal drug release, reaching an impressive 97% over 20 hours. The stability studies performed on F5 revealed no notable alterations within three months under ICH conditions, thus verifying the formulation's strength. The results suggest that the improved formulation can improve patient adherence and maximize drug absorption, offering promising advantages in the effective treatment of hypertension through prolonged medication effectiveness.
Isatin and its Analogues as Promising Biological Agents
(Book Rivers, 2026) Mohd Arsh Khan, Ziaul Husain, Sabahat Yameen Sheikh, Firoj Hassan
The synthesis of isatin derivatives hold significant potential in various fields, particularly in pharmaceuticals and materials science. The synthesis of isatin derivatives represents a significant area of research with promising implications across various fields including medicinal chemistry, materials science, and organic synthesis. Through this, we have delved into the intricate methodologies and strategies employed in the synthesis of these compounds, aiming to provide a comprehensive overview of the advancements, challenges, and future prospects in this domain. Our investigation began with an exploration of the significance of isatin derivatives, highlighting their diverse biological activities and potential therapeutic applications. Structure-activity relationship (SAR) analysis was conducted to correlate the chemical modifications with observed biological activities, providing a foundation for future optimization and development. In conclusion, this chapter contributes to the growing body of knowledge on isatin chemistry, offering new insights into the synthesis, and potential applications. The findings underscore the importance of tailored chemical modifications in enhancing the properties and functionalities of isatin-based compounds.
AZOLE DERIVATIVES AND THEIR BIOLOGICAL ACTIVITIES
(Book Rivers, 2026) Vaishnavi Dubey, Mohd Arsh Khan, Neda Fatima, Sabahat Yasmeen Sheikh, Firoj Hassan
Azoles, a significant category of nitrogen-containing heterocycles, have attracted considerable interest in medicinal chemistry due to their structural flexibility, capacity to form hydrogen bonds, and diverse biological effects. This chapter delves deeply into azole derivatives, highlighting their synthesis and their importance in pharmacology. Azoles, such as imidazole and benzimidazole derivatives, are renowned for their significant contribution to the advancement of antifungal, anticancer, and antimicrobial medications. The chapter explores various synthetic methods, including Williamson etherification and regioselective nucleophilic ring-opening reactions, used to produce coumarin-based azole derivatives. These derivatives exhibit remarkable therapeutic properties due to their distinct structural features and interactions with biological targets. Furthermore, the crucial role of nitrogen heterocycles in FDA-approved medications is highlighted, underscoring their extensive use in the development and manufacture of drugs. This chapter highlights the vital role of nitrogen-containing heterocycles in contemporary pharmacology and their ability to tackle a wide range of medical issues through showcasing examples of clinically approved drugs and recent breakthroughs.
21 वीं सदी मे समावेशी शिक्षा और शिक्षक की चुनौतियाँ
(Evincepub Publishing, 2026) Rakesh Kumar
21वीं सदी में शिक्षा का स्वरूप तेजी से बदल रहा है, जहाँ समावेशिता (Inclusion), समानता (Equity) और गुणवत्ता (Quality) को विशेष महत्व दिया जा रहा है। समावेशी शिक्षा का उद्देश्य यह सुनिश्चित करना है कि सभी विद्यार्थी - चाहे वे किसी भी सामाजिक, आर्थिक, सांस्कृतिक या शारीरिक-मानसिक पृष्ठभूमि से हों एक समान और गुणवत्तापूर्ण शिक्षा प्राप्त कर सकें। इस अध्याय में 21वीं सदी के संदर्भ में समावेशी शिक्षा की अवधारणा, इसके उद्देश्य, तथा शिक्षकों के सामने आने वाली प्रमुख चुनौतियों का गहन विश्लेषण किया गया है। साथ ही, इन चुनौतियों के समाधान हेतु व्यावहारिक उपायों और नीतिगत सुझावों को भी प्रस्तुत किया गया है। अध्ययन से स्पष्ट होता है कि समावेशी शिक्षा की सफलता में शिक्षक की भूमिका केंद्रीय और निर्णायक है, जिसके लिए उन्हें तकनीकी, शैक्षणिक और भावनात्मक रूप से सशक्त बनाना आवश्यक है (UNESCO, 2005; ΝΕΡ, 2020) |
Tourism as Soft Power: A Political-Economic Theory of Cultural Capital and Regional Development in India
(Indu Book Services Pvt. Ltd., 2026) Mohd. Faiz, Dr. Amjad Kamal ,Imran, Tahir Hussain Ansari, Mohd Anas Wajid
Against the backdrop of a volatile global order, this study reconfigures the discourse on Indian tourism, positioning it not merely as a tertiary service sector but as a dual-engine of soft power projection and regional structural transformation. Deploying a novel political-economic framework that synthesizes Joseph Nye’s soft power paradigm with Pierre Bourdieu’s theory of cultural capital, the research identifies a specific “conversion mechanism” wherein intangible heritage assets, spanning UNESCO enclaves and syncretic festivals, are transmuted into tangible diplomatic influence and decentralized economic equity. Empirical analysis of the sector’s post-pandemic “V-shaped” recovery supports a linear projection model suggesting that Foreign Exchange Earnings (FEEs) could potentially double by 2029, validating the sector’s capacity to function as a hard-economic pillar of statecraft. By examining policy interventions like the Swadesh Darshan scheme, the paper demonstrates how tourism acts as an interstitial development force, generating employment in peripheral regions while embedding Indian cultural narratives within bilateral ties. However, the study cautions against the risks of “cultural commodification,” proposing a “cultural equity index” and participatory governance models to ensure that economic ascendancy does not erode the authenticity of the very assets it leverages. Ultimately, this framework establishes tourism as the vanguard of India’s trajectory toward Viksit Bharat, harmonizing civilizational resonance with inclusive 21st- century economic growth.