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Antitubercular Potential of Bioactive Phytoconstituents from Andrographis Paniculata: Targeting DprE1 of Mycobacterium Tuberculosis
(Zenodo, 2026) Samar Mujeeb1, Farhat Aisha Ansari
Tuberculosis (TB) remains one of the leading infectious diseases worldwide, and the emergence of multidrug-resistant strains has intensified the need for novel therapeutic agents. Medicinal plants continue to provide structurally diverse bioactive molecules with significant drug discovery potential. Andrographis paniculata (Kalmegh) is widely recognized for its antimicrobial and immunomodulatory activities and may represent a promising source of antitubercular lead compounds.
Phytochemical Innovations and their Therapeutic Role in Neurodegenerative Disorders
(Zenodo, 2026) Farhat Aisha Ansari, B. Ali Modu, Samar Mujeeb
Neurodegenerative disorders such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and Huntington’s disease (HD) are progressive neurological conditions associated with cognitive decline, neuronal loss, and impaired quality of life. The increasing prevalence of these disorders and the limitations of existing therapeutic options have encouraged exploration of medicinal plants as alternative neuroprotective agents. The objective of this study is to examine current trends in medicinal plant research and evaluate their therapeutic relevance in neurodegenerative disorders. The methodology involved a narrative review and scientific evaluation of published literature focused on medicinal plants, phytochemicals, ethnopharmacological evidence, and molecular mechanisms associated with neuroprotection. Data from recent studies were analyzed to identify major bioactive compounds and their mechanisms of action.
The findings indicate that medicinal plants and plant-derived compounds demonstrate significant neuroprotective activities through antioxidant, anti-inflammatory, anti-apoptotic, and signaling pathway modulation mechanisms. Bioactive constituents including flavonoids, polyphenols, alkaloids, and terpenoids have shown the ability to regulate oxidative stress, mitochondrial dysfunction, protein aggregation, and neuroinflammation. Several medicinal plants including Bacopa monnieri, Ginkgo biloba, Panax ginseng, and Centella asiatica have exhibited promising therapeutic outcomes in experimental and preclinical studies.
In conclusion, medicinal plant research offers a promising direction for developing safer and multi-target therapeutic strategies for neurodegenerative disorders. Integration of traditional medicinal knowledge with modern pharmacological approaches may support future advancements in neuroprotective drug discovery.
Living the Norms: Philosophical Reflections on Life, Law and Morality
(Viva Books Private Limited, 2026) Mirza Juned Beg
Ensuring Climate Justice for all and International Environmental Politics: Interconnection between Humanity and Nature in a Globalized World
(Dr. Ram Manohar Lohia National Law University, Lucknow, 2022) Mirza Juned Beg, Mohd Sufiyan Khan
In contemporary period, the preservation of mother earth is a key issue all over the globe. Environment composed of both physical and biological components. Only single nation's dreadful conditions of environmental degradation may affect the worldwide ecosystem for all the nations. The crisis of enviro-crimes has attained global dimension and India is not immune from this crisis.
The climate change has been a key theme in global relations for nearly half a century now. Characteristically of a trans-national climate issues have been acknowledged as an archetypal strategy domain for global collaboration interests, ideas and organizations play out at the international arena that shape the who gets what in this international domain. Therefore, in recent years, International Environmental Jurisprudence is being increasingly witnesses as a serious means of promoting Sustainable Development Principles at global sphere.
The authors in this paper deals with the challenges and issues relating to ensuring Climate Justice for all and International Green Politics, role of International Institutions and various concern agencies and what are the international policies and guidelines for the protection and restoration of environment.
Artificial Intelligence (AI) in Renewable Energy Systems: A Brief Overview for Conserving and Efficiently Utilizing Renewable Resources
(Taylor & Francis CRC Press, 2026) Nupur Mittal, ImranUllah Khan, Zohaib Hasan Khan, Farooq Ahmad, Mohd Amir Ansari
The global energy demand is anticipated to grow at an average annual rate of 8% from 2000 to 2030. Fossil fuels currently supply a significant portion of this energy, having profound impacts. Renewable energy (RE) sources are gaining popularity as alternatives to fossil fuels for various reasons. However, the transition to RE sources is critical for addressing climate change and reducing dependence on fossil fuels. However, the variability and intermittency of RE present significant challenges for efficient utilization and integration into power grids. Artificial intelligence (AI) and machine learning (ML) are relatively new concepts in the energy sector. The proposed work highlights how AI can optimize the generation and distribution of RE through predictive analytics and ML models. This chapter explores the role of AI in enhancing the efficiency and reliability of RE systems (RES), including solar, wind, hydro, and bioenergy. The work explores the contribution of AI to improving energy storage. The proposed work emphasizes the role of AI in improving energy efficiency and conservation. The synergy between AI and RES offers innovative pathways to conserve resources and promote sustainable energy practices.