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The Multidisciplinary Pervasive Face of Business Management
(Book Rivers, 2026) Rizwana Atiq, Firoz Husain, Priyanka Bajpai
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Isolation, purification, and challenges in extracellular vesicles
(Elsevier, 2026) Sumel Ashique , Anas Islam , Yusuf Asad
A subclass of extracellular vesicles (EVs), known as exosomes, has proven to be an effective therapeutic tool for treating a range of illnesses. EVs are nanoscale vesicle structures that are released by many types of cells. They are involved in cell signal transduction, carry a multitude of biological macromolecules, and evade immune system clearance. Exosomes are abundant in all living things and are secreted by practically all cells, which make them great candidates for a wide range of studies and applications. There are four main procedures used to isolate exosomes: centrifugation, precipitation, ultrafiltration, and immunoassay. Their primary goal is to rid the exosomes of the mixed cells, their pieces, and other tiny molecular contaminants. Nonetheless, the isolation of exosomes is extremely difficult due to their intrinsic variability, the complexity of biological fluids, and the existence of nanoscale pollutants. Conventional exosome isolation techniques are laborious, difficult, and require lengthy, intricate procedures. The development of nanolithography, electrodeposition, microfluidic chips, and other technologies has encouraged the fusion and innovation of isolation techniques. The utilization of these techniques has resulted in significant advantages for exosome isolation, including ultrafast, portable integration, and minimal loss. Clinical applications, isolation purity, and isolation yield have all seen notable functional advances.
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Unraveling platelets’ dual role: Bridging inflammation and cancer toward innovative therapeutic strategies
(Elsevier, 2026) Utpal Bhui , Sumel Ashique , Radheshyam Pal , Tahreen Taj , Anas Islam , Farzad Taghizadeh-Hesary , Neeraj Mishra
Platelets are the components that are traditionally used for maintaining homeostasis, derived from the megakaryocytic. The recent research development of platelets shows an interesting result in the modulation of immune response, inflammation, and tumor treatment. Platelet activation is a sequential process that is tightly controlled by a variety of receptors, signaling molecules, and intracellular pathways. However, the formation of platelet aggregation is a useful biomarker for systematic inflammation. Moreover, malignant cells can induce activation of platelet through the discharge of prothrombotic factors, namely, tissue factor and cancer procoagulant. Once activated, platelets aggregate around tumor cells, forming a protective shield that prevents immune cells from recognizing and destroying the tumor. Some of the antiplatelet agents, including aspirin and P2Y12 inhibitors, are extensively used for preventing cardiovascular diseases; however, studies performed recently have shown that they may also have potential in cancer therapy. Targeting new approaches for the platelets could emerge the therapeutic activity not only for the chronic inflammation but also for the disruption of cancer progression. However, new approaches like the treatment through platelets may cause serious complications, but future research can lead to targeted treatments, which offer the potential therapeutic approaches in improving patient outcomes in both inflammatory diseases and cancer.
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Retail Competition and Market Dynamics: A Case Study of Mother Dairy in Lucknow
(Book Rivers, 2026) Faheem Khan, Abdul Tayyab Khan
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Shaping India’s Future: Start-ups, Sustainability & Strategic Transformation
(Book Rivers, 2026) Abdul Tayyab Khan, Orooj Siddiqui
Shaping India’s Future: Start-ups, Sustainability & Strategic Transformation explores the role of innovation, entrepreneurship, sustainability, and digital transformation in shaping India’s evolving socio-economic landscape. The book examines key themes such as Artificial Intelligence, Corporate Social Responsibility (CSR), influencer marketing, augmented reality, healthcare innovation, and public-private partnerships through conceptual discussions, case studies, and contemporary examples. It highlights how technology-driven strategies and sustainable business practices contribute to inclusive growth, governance efficiency, and strategic development in India. The volume serves as a valuable resource for researchers, students, policymakers, and business professionals interested in innovation and sustainable transformation.