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From Yogic Psychology to Educational Practice: A Conceptual Framework Linking Chitta-Vritti-Nirodha, Attention Regulation, and Meaningful Learning
(Asian Journal of Education and Social Studies, 2026) Dhriti Tiwari
The possibility that contemplative disciplines can strengthen attention and thereby support learning has attracted interest across educational psychology, cognitive neuroscience and school-based yoga research. Yet the classical formulation yogaś citta-vṛtti-nirodhaḥ addresses an ethical and soteriological project, not a validated theory of academic performance. This critical narrative review examines the conceptual distance and potential connections between Pātañjala yoga psychology, experimentally studied attention regulation and meaningful learning. Relevant philosophical analysis, cognitive and educational theory, intervention trials and research syntheses were evaluated with particular attention to construct correspondence, comparison conditions, developmental context, educational outcomes and ethical implementation. The evidence supports a conditional, rather than direct, link: contemplative exercises may sometimes improve proximal attentional or emotional-regulatory processes, but improved performance on attention tasks does not establish durable understanding, conceptual change or transfer. School-based syntheses report heterogeneous and generally small benefits, with weaker or absent advantages against active controls and inconsistent effects on achievement. The proposed framework therefore distinguishes philosophical orientation, trainable regulatory practices, cognitive mediators, task-specific engagement, pedagogical mechanisms and learning outcomes. It treats curricular quality, learner agency, developmental suitability and sociocultural context as necessary moderators rather than incidental details. Four falsifiable pathways are advanced, while a competing explanation attributes some observed gains to movement, structured pauses, adult attention or expectancy. The review concludes that contemplative attention training is best understood as an optional enabling condition for well-designed learning activities, not as an alternative to explanation, retrieval, feedback, conceptual discussion or equitable teaching. Research should test mechanisms, potential harms and durable transfer through preregistered active-comparator studies using both attentional and curriculum-aligned measures.
Cell Growth Regulation and Molecular Targets of Lupeol
(CRC Press (Taylor & Francis Group), 2026) Sana Parveen, Mariyam Fatma, Snober S. Mir
Lupeol, a pentacyclic triterpene found in various fruits and vegetables, has garnered significant attention for its multifaceted therapeutic potential, particularly in cancer treatment. Its molecular targets and mechanisms of action have been extensively studied, revealing its role as an effective anticancer agent through various pathways. Lupeol modulates apoptosis and proliferation signaling pathways to fight cancer. Lupeol affects cell cycle regulatory proteins to promote apoptosis in prostate, breast, and liver cancer cell lines. Lupeol leads to G2/M phase arrest and death in prostate cancer cells (PC3 and DU145) by suppressing NF-κB activation and downregulating β-catenin signaling. Lupeol can also limit tumor growth and promote apoptosis by suppressing the STAT3 signaling pathway, which is elevated in many malignancies. Lupeol effectively targets the Wnt/β-catenin and PI3K/Akt/mTOR pathways, essential for cell survival and growth. The dual effect of lupeol on cancer cell signaling and anti-inflammatory qualities may help fight cancer. It alters the expression of pro-inflammatory cytokines, including IL-6 and TNF-α, which are increased in the tumor microenvironment and contribute to cancer growth. The medicinal potential of lupeol goes beyond cancer. Its antioxidant and androgen receptor inhibitor properties make it a prospective treatment for androgen-dependent malignancies like prostate cancer. So, lupeol acts on multiple molecular targets and pathways, including apoptosis regulation, cell cycle arrest, and inflammatory response modulation, making it a versatile compound in cancer therapy. Its ability to inhibit key signaling pathways associated with tumor growth and survival underscores its potential as a therapeutic agent in various malignancies.
Roles of Lupeol-Rich Food on Gut Microbiota and Postbiotics in Human Diseases
(CRC Press (Taylor & Francis Group), 2026) Mohd Aamir Qureshi, Shahper Nazeer Khan, Saleem Javed, Snober S Mir
The complex interactions among food, gut microbiota, and human health have emerged as a primary area of research in recent decades. Bioactive chemicals, especially those sourced from plants, exhibit considerable potential in altering gut microbiota composition and function, thus affecting many physiological processes and disease outcomes. Lupeol, a natural triterpenoid prevalent in fruits, vegetables, and medicinal plants, has attracted interest due to its various biological roles. Lupeol, traditionally utilized in global medicinal systems, has been scientifically corroborated for its anti-inflammatory, antioxidant, anticancer, cardioprotective, and antidiabetic attributes. The therapeutic efficacy of lupeol, its bioavailability and distribution is essential for host metabolism, immunological response, and overall well-being. The gut microbiota is disrupted in dysbiosis, which is linked to neurological issues, metabolic disorders, cardiovascular diseases, and inflammatory bowels. This chapter examines different sources of lupeol and how diets high in lupeol may generate advantageous postbiotics, such as short-chain fatty acids and other microbial metabolites. By comprehending these connections, the diatery interventions can be enhanced to foster gut health and address or avert particular pathological disorders. This chapter also discusses lupeol meadiated activation of various metabolic pathways and cell signaling that manages chronic diseases and enhancing precision nutrition, offering insights into innovative strategies for improving human health by dietary modifications
Data analysis using high-throughput sequencing technologies and bioinformatics tools
(Academic Press, Elsevier, 2026) Mohd Aamir Qureshi , Umamah Siddiqui, Shahper Nazeer Khan
The advent of high-throughput sequencing (HTS) technologies has revolutionized microbiome research, enabling unprecedented insights into microbial communities and their roles in health and disease. This chapter provides a comprehensive overview of data analysis approaches for microbiome studies, emphasizing the integration of next-generation sequencing technologies with sophisticated bioinformatics tools. We explore the applications of 16S rRNA gene sequencing for taxonomic profiling, particularly in cancer microbiome studies, where microbial dysbiosis plays crucial roles in tumor development and therapeutic responses. The chapter details PCR-based amplification strategies and their limitations, contrasting them with shotgun metagenomics approaches that provide comprehensive genomic analysis capabilities. We examine computational methodologies essential for processing large-scale microbiome datasets, including quality control, taxonomic assignment, diversity analysis, and functional annotation. The chapter addresses current challenges in microbiome bioinformatics, including standardization issues and statistical considerations for multiomics integration. Emerging technologies and future directions are also explored, providing readers with practical guidance for selecting appropriate analytical approaches. This chapter also provides a comprehensive overview of sequencing technologies, from second-generation platforms such as Illumina, Roche 454 pyrosequencing, and Ion Torrent to third-generation technologies, including Oxford Nanopore. This comprehensive resource serves as a practical guide for researchers seeking to leverage HTS data for microbiome analysis across diverse biological systems.
संस्कृतियों का सेतु, ह्रदय का संगम और विविधता में एकता का पथ
(Book Rivers, 2026) एम् यू राजा, उमा पांडेय
प्राचीन भारतीय ज्ञान प्रणालियों और समकालीन प्रवृत्तियों का प्रतिच्छेदन, विशेष रूप से योग के क्षेत्र में, एक आकर्षक प्रवचन का प्रतीक है जो वैश्विक स्तर पर गूंजता है। यह भारतीय ज्ञान प्रणालियों के बहुआयामी आयामों और उनके गतिशील विकास पर गहराई से विचार करता है, जिसमें आधुनिक युग में योग की स्थायी प्रासंगिकता और अनुकूलन पर विशेष ध्यान दिया गया है। ऐतिहासिक जड़ों, दार्शनिक आधारों, वैज्ञानिक प्रगति, सामाजिक-सांस्कृतिक निहितार्थों और व्यावसायीकरण की गतिशीलता की व्यापक खोज के माध्यम से, यह अध्ययन उस जटिल ताने-बाने को उजागर करने का प्रयास करता है जो परंपरा और नवाचार को एक साथ जोड़ता है। योग भारतीय ज्ञान प्रणालियों का सबसे व्यापक रूप से मान्यता प्राप्त और प्रचलित पहलू है, जो परंपरा और आधुनिकता के संश्लेषण को समझने के लिए एक केंद्र बिंदु के रूप में कार्य करता है। पतंजलि के योग सूत्र जैसे प्राचीन ग्रंथों में इसकी उत्पत्ति से लेकर दुनिया भर के स्टूडियो, जिम और वेलनेस सेंटरों में इसकी समकालीन अभिव्यक्तियों तक, योग ने व्यक्तिगत और सामाजिक परिवर्तन के लिए एक समग्र प्रणाली के रूप में अपने सार को बनाए रखते हुए एक उल्लेखनीय परिवर्तन किया है। आसन, प्राणायाम, ध्यान और माइंडफुलनेस तकनीकों सहित विविध योग प्रथाओं के विश्लेषण के माध्यम से। यह अध्याय उन अंतर्निहित सिद्धांतों को उजागर करने का प्रयास करता है जो समग्र कल्याण की खोज में परंपरा को नवाचार के साथ जोड़ते हैं।