Research Articles/ Conferences

Permanent URI for this collectionhttp://192.168.24.11:4000/handle/123456789/58

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Impact of Institutional Repositories’ on Scholarly Practices of Scientists
(Library Philosophy and Practice University of Nebraska, 2018-02-01) Shukla, Prachi; Ahmad, Naved
Novel drug design and bioinformatics: an introduction
(De Gruyter, 2021) Mohammad Kalim Ahmad Khan ,Salman Akhtar
In the current era of high-throughput technology, where enormous amounts of biological data are generated day by day via various sequencing projects, thereby the staggering volume of biological targets deciphered. The discovery of new chemical entities and bioisosteres of relatively low molecular weight has been gaining high momentum in the pharmacopoeia, and traditional combinatorial design wherein chemical structure is used as an initial template for enhancing efficacy pharmacokinetic selectivity properties. Once the compound is identified, it undergoes ADMET filtration to ensure whether it has toxic and mutagenic properties or not. If the compound has no toxicity and mutagenicity is either considered a potential lead molecule. Understanding the mechanism of lead molecules with various biological targets is imperative to advance related functions for drug discovery and development. Notwithstanding, a tedious and costly process, taking around 10–15 years and costing around $4 billion, cascaded approached of Bioinformatics and Computational biology viz., structure-based drug design (SBDD) and cognate ligand-based drug design (LBDD) respectively rely on the availability of 3D structure of target biomacromolecules and vice versa has made this process easy and approachable. SBDD encompasses homology modelling, ligand docking, fragment-based drug design and molecular dynamics, while LBDD deals with pharmacophore mapping, QSAR, and similarity search. All the computational methods discussed herein, whether for target identification or novel ligand discovery, continuously evolve and facilitate cost-effective and reliable outcomes in an era of overwhelming data.
Security Test Case Prioritization through Ant Colony Optimization Algorithm
(Tech Science Press, 2023) Mohd Faizan; Mohd Waris Khan; Abdulaziz Attaallah, Khalil al-Sulbi, Areej Alasiry, Mehrez Marzougui, Alka Agrawal, Dhirendra Pandey
Security testing is a critical concern for organizations worldwide due to the potential financial setbacks and damage to reputation caused by insecure software systems. One of the challenges in software security testing is test case prioritization, which aims to reduce redundancy in fault occurrences when executing test suites. By effectively applying test case prioritization, both the time and cost required for developing secure software can be reduced. This paper proposes a test case prioritization technique based on the Ant Colony Optimization (ACO) algorithm, a metaheuristic approach. The performance of the ACO-based technique is evaluated using the Average Percentage of Fault Detection (APFD) metric, comparing it with traditional techniques. It has been applied to a Mobile Payment Wallet application to validate the proposed approach. The results demonstrate that the proposed technique outperforms the traditional techniques in terms of the APFD metric. The ACO-based technique achieves an APFD of approximately 76%, two percent higher than the second-best optimal ordering technique. These findings suggest that metaheuristic-based prioritization techniques can effectively identify the best test cases, saving time and improving software security overall.
Revolutionizing the Oil and Gas Industry through Nanotechnology
(Proceedings of the International Conference on the topic “Innovative approaches to localization, 2023) Sabeeha Jabeen, Shashi Bala, Abdul Rahman Khan, Tahmeena Khan
Nanotechnology has the potential to change the technological landscape of the oil and gas industry. Current research is exploring the use of nanotechnology in different aspects related to the oil and gas industry. This review summarizes the research advances in the field of drilling and processing and, the development/improvement of oil recovery using nanotechnology. Such information can help researchers understand current research and expand the applications of existing nanomaterials and elucidating the special properties of nanomaterials will continue to increase the use of nanomaterials in the oil petroleum and natural gas sectors.
APPLICATION OF NANOTECHNOLOGY IN FOOD PROCESSING AND PACKAGING
(RESEARCH PROCEEDINGS OF INTERNATIONAL FORUM TASHKENT,, 2023) Sabeeha Jabeen, Shashi Bala, Abdul Rahman Khan, Tahmeena Khan
Nanotechnology comprises the wide-ranging application in food industries, such as packaging, and processing of food materials at the nanometer scale. The exploration of nanostructured materials in food industries are continue for processing and packaging purposes. Existing finding methods for food processing and packaging are expensive and time-taking and needs innovative technologies. Novelties in, nano-processing, and nano-packaging, are the current developments in the food sector. The amalgamation of nanotechnology with the food engineering industries and food packing industries now improved the excellence of foodstuff. The newest noteworthy investigation and improvement in the application of nanostructured-dependent packing of food items and processing is an antimicrobial application to detect spoilage and prevent food. Nanostructured materials are now striking findings in food packing systems as their enhanced useful properties like mechanical strength and barricading properties even own antimicrobic and antioxidant actions to preserve the excellence and range the shelf life in numerous food applications. Numerous nanostructured materials (silicate nano clay, metal oxide nanostructures, and polymer-based nanocomposites) are now involved in food packing systems. This Article will highlight the current nanostructured material in packaging and food processing applications together with food safety.
BEYOND BARRIERS: A TAPESTRY OF PEDAGOGICAL STRATEGIES FOR INCLUSIVITY AND SUSTAINABLE PROGRESS
(International Journal of Emerging Knowledge Studies, 2024) Dhriti Tiwari
In an ever-evolving landscape of education, the imperative to foster inclusivity and sustainable progress stands as a foundational challenge for educators worldwide. The present age, marked by an unparalleled range of differences, educators are faced with the task of adapting their methodologies to accommodate the distinct requirements and inclinations of a diverse student population. Concurrently, the increasing worldwide demand for sustainable practices underscores the imperative to incorporate environmental consciousness and responsible civic engagement into the core of educational systems. This research article explores innovative educational approaches that go beyond traditional boundaries to foster comprehensive and long-lasting progress. It examines the integration of differentiated instruction, universal design for learning, and collaborative learning in a harmonious and inclusive learning environment. The study also explores a tapestry of pedagogical approaches for accommodating diverse learning needs and addressing 21st-century challenges. Cultural responsiveness, environmental education, and technological integration are key to sustainability and inclusivity. The research shows that these pedagogical practices can change education for the betterment of students and the world.
A study on perceptions and practices of STEAM-based education with university students
(Social Sciences & Humanities Open, 2024) Manisha Singh
The present survey-based study was conducted with (n = 317) university students in Lucknow city of India to examine their perceptions and practices about Science, Technology, Engineering, Arts, and Mathematics (STEAM) education. The data was collected from students belongingto different academic streams including Science, Economics, Arts, Engineering, Architecture, Computer Sciences, and Business and Management etc. from different higher educational institutions of the city. The snowball sampling method was adopted for the study. A tool in the form of a 5-pointer rating scale with three categories viz. Awareness, Perception and Implementation along with two dimensions in the Awareness category, four dimensions in the Perception category and one dimension in the Implementation category was constructed to collect data with a total of 23 items which were related to majorly three mentioned categories and demographic information. Frequency data analysis and the Kruskal-Wallis H test were used for analysis. The findings showed that most students hold a positive perspective towards the advantages of STEAM in their learning process. Still, despite the positive perspective, significant differences in the perception and implementation category of STEAM-based education was seen. The teaching-learning process is not planned as per STEAM education and classroom teaching lacks in in-cooperating STEAM. A significant difference was observed in the perception and implementation of STEAM-based education. The study showed that more than 70 per cent of the students believed that STEAM-based Education may enhance deeper understanding, constructivist approach, professional efficiency and critical thinking. The findings also highlighted the positive role of STEAM Education in infusing aesthetic elements and holistic approach in students.
Assessing the Impact of Human-Induced Disturbances on the potential Biomass and Carbon content in two wildlife sanctuaries of Uttar Pradesh, India
(EM International, 2024) Azram Tahoor, Azra Musavi, Jamal Ahmad Khan
This research paper presents a detailed analysis of biomass assessment of woody species in Katerniaghat and Kaimoor Wildlife Sanctuary situated in Bahraich and Mirzapur district of Uttar Pradesh. Through a reconnaissance survey, area was stratified into high, medium and low disturbed site based on the presence of human induced disturbance indicators. Circular plot method of 10m radius was used for vegetation assessment. Data on vegetation like woody species name, number of individuals, Girth at Breast’s height were recorded. Biomass and carbon stock of tree species was calculated from each stratified site of both sanctuaries. The finding of the study showed that highest biomass was estimated from high disturbed site of Katerniaghat. In Kaimoor, medium disturbed site showed maximum biomass. The present study aims to provide a comprehensive understanding of its carbon stock and sequestration potential. Biomass assessment is crucial for sustainable forest management and climate change mitigation strategies. Our findings reveals the negative impact of varying levels of anthropogenic disturbance on the forest biomass of both protected areas and help in better understanding of conservation and management and forests and carbon offset initiatives.
Nanoconjugation of Schiff Bases for Biological Activity Enhancement
(Zenodo, 2024) Ekhlakh Veg, Sabeeha Jabeen, Seema Joshi, Tahmeena Khan
Schiff bases form metal chelates which show good antimicrobial, anticancer properties etc. Due to poor solubility, poor bioavailability, researchers now conjugated these Schiff bases to nanoparticles which enhance the solubility and bioavailability for better results. This paper reports the nanocojugation of Schiff bases and their diverse biological activities. Keywords: Schiff bases, Antimicrobial, anticancer, nanoparticles etc.
CuO NANOPARTCLES AND THEIR ANTIBACTERIAL ACTIVITY EVALUATION
(Zenodo, 2024) Sabeeha Jabeen, Ekhlakh Veg, Shashi Bala, Seema Joshi, Tahmeena Khan
The development of antibiotic resistance is one of the most pressing problems in global healthcare. Microbial resistance to antibiotics might be combatted by the use metal-oxide-based nanoparticles (NPs). Many studies have shown that Copper oxide nanoparticles (CuO NPs) have potent antibacterial activity against different Gram-positive and Gram-negative bacteria. This review summarizes some recent studies to investigate the antibacterial activity of the CuO NPs fabricated from different strategies, particularly green synthesis which has emerged as an environment-friendly approach for the fabrication of NPs.
Microbial-Assisted Green Synthesis of Zinc Oxide Nanoparticles and their Potential Application
(Zenodo, 2024) Ekhlakh Veg, Sabeeha Jabeen, Seema Joshi, Tahmeena Khan
Nanomaterials are the rapidly growing field of nanotechnology. The development of reliable strategies for the synthesis of nanomaterials with different chemical compositions, sizes, and high monodispersity is one of the most challenging issues these days. Recent studies on the use of microorganisms in the synthesis of nanoparticles (NPs) are a relatively new and exciting area of research with considerable potential for development. This mini-review highlights the use of different microorganisms in the biosynthesis of zinc oxide nanoparticles (ZnO NPs) and their biological applications.
Metal Oxide Nanoparticles in Environmental and Industrial Microbiology
(Zenodo, 2024) Sabeeha Jabeen, Ekhlakh Veg, Shashi Bala, Tahmeena Khan
Metal oxide-based nanoparticles (NPs) have numerous applications in science and technology. This paper focuses on applications of NPs Environmental and Industrial Microbiology. Metal oxide-based NPs find applications in wastewater remediation, gas sensing, and heavy metal eradication because of their non-toxic behavior, large surface area, bandgap, and tremendous catalytic performance. Attainment of selective nanostructures of metal oxide nanoparticles is possible through the green synthetic methodology without generating any toxic by-products. These properties make them effective in applications ranging from pollution control and bioremediation to industrial processes like biofuel production and antimicrobial surface creation. However, the potential toxicity of these NPs and their long-term environmental impact pose significant challenges. This Paper highlights the promise of metal oxide NPs in advancing microbiology while underscoring the need for comprehensive risk assessments to ensure their safe application.
EXPLORING THE POTENTIAL USE OF CHALCONES IN AGRICULTURE
(INTERNATIONAL SCIENTIFIC AND PRACTICAL CONFERENCE, 2024) Haroon Ahmad Khan, Saimah Khan
Chalcones are naturally occurring flavonoid compounds and have recently been elucidated to display a vast spectrum of biological activities such as antifungal, antibacterial, herbicidal, and insecticidal activities. Due to their α, β-unsaturated carbonyl system their structure forms a basis for several bioactivities making them ideal in crop protection. This short review aims at discussing modern agricultural application of chalcones including synthesis and biological impact as well as the potential application in the future. As demand for environment friendly approaches to control pests and diseases are on the rise, chalcones offers a good chance of developing green agrochemicals.
Balancing Faith and Learning : A Systematic Review on Faith-Based Curriculum in Catholic Schools
(TPM(Testing, Psychometrics, Methodology in Applied Psychology), 2025)
Education in Catholic Schools uses faith-based approaches to nurture students morally, intellectually, and ethically for their holistic growth. Catholic Education aims at nurturing the student from all backgrounds, combining faith with schooling. Such an approach also tries to deal with opposing secularization, lack of trained staff, and teacher training constraints alongside dealing with contemporary education challenges.Teaching from a faith-based educational approach is examined and so are the challenges involved through the learner focusing on the moral and character development, teacher perception, and student perception in the Catholic School context. This review literature is comprehensive and employs the PRISMA framework to identify relevant studies focused on the outcomes of a faith-based approach to education in Catholic schools. We searched between 2004-2024 across multiple databases, including J Gate, JSTOR, Science Direct,ScopusProQuest. Initially, 968 studies were obtained, and after screening titles/abstracts, applying eligibility criteria, and assessing full texts, 26studies were selected for detailed analysis.
Supply Chain Transparency as a Marketing Differentiator in Healthcare: Advacing Responsible Consumption and Production under SDG 12
(Széchenyi István University, Győr, Hungary, 2025) Rizwana Atiq , Shahab Ud Din
Sustainability in Practice: Understanding the Intention-Behavior Gap Among Middle-Class Consumers in Lucknow
(Széchenyi István University, Győr, Hungary, 2025) Firoz Husain, Rizwana Atiq
Impact of Microblogging Platform on Investment Decisions in Retirement and Pension Products
(AKG GLOBAL SUPPORT SERVICES (OPC) PRIVATE LIMITED, 2025) Mohammad Gayas Ansari, Afreen Fatima
This research paper seeks to analyse the effects of microblogging, particularly involving websites like twitter and reddit, on investment decisions especially as they relate to retirement and pension. With the new digital interfaces helping the user to surf the internet more and more, microblogging sites have become important public spheres where individual investors, financial advisors, stock market experts and others are expressing opinions and analysis. This paper seeks to understand the implications and impact of the content shared on these platforms to investors’ decision making, perceived risk and confidence in retirement solutions. In this research, social media posts with topics on retirement investment are analyzed qualitatively while quantitative surveys are conducted on individual investors. The study reveals that microblogging platforms affect investors’ decisions in relation to perceived financial gains and implicated risks. But at the same time, this work also reveals threats resulting from increased influence of fake news and its instability factor and differing in content. The findings can be useful for financial planners, government officials and shareholders interested in exploring the impact of microblogging for decisions related to retirement investment and the possibility of using social media in raising people’s financial literacy and increasing their awareness.
Identifying EphA2-Targeted Lead Compound in Breast Cancer
(IJERT, 2025) Mohd Nehal, Jahanarah Khatoon, Salman Akhtar, Mohammad Kalim Ahmad Khan
Ephrin Type-A receptor 2 (EphA2) plays a crucial role in breast cancer cell survival and proliferation, making it a promising therapeutic target. EphA2 overexpression is associated with poor prognosis and metastatic behavior in melanoma, lung, prostate, brain, breast cancer, and leukemia. In silico analysis identified Mcule- 8617639093 as a potent EphA2 inhibitor. Through proliferation assays targeting EphA2 in MDA-MB-231 breast cancer cells, we found that the virtually identified lead molecule significantly bound to EphA2- overexpressing breast cancer cells at different concentrations. The efficacy of the compound was validated using MTT assays and annexin-V/PI staining. These findings contribute to the development of EphA2- targeted therapies.
The Association of Social Media with Anger and Psychological Well-Being Among Users and Non-Users
(The International Journal of Indian Psychology, 2025) Om Pandey, Deepa Pandey, Jyotsana Shukla
This study investigates the impact of social media usage on anger and psychological well- being by comparing users and non-users. Using standardized psychological measures, including the Bergen Social Media Addiction Scale, Buss-Perry Aggression Questionnaire, and Ryff's Psychological Well-Being Scale, the research assesses the relationship between social media engagement, aggression, and emotional health. Data analysis reveals a significant positive correlation between social media usage and aggression (r = 0.499, p < 0.01), indicating that frequent users exhibit higher levels of anger. Additionally, a strong negative correlation between social media use and psychological well-being (r = -0.548, p < 0.01) suggests that excessive online engagement contributes to lower emotional stability and life satisfaction. In contrast, non-users demonstrate lower aggression levels and greater psychological well-being.
The Effect of Homoeopathic Medicine in Management of Psychological Distress in Gynecological Problems- A Pilot Study
(The International Journal of Indian Psychology, 2025) Shikha Chouhan, Deepa Pandey, Madhu Pandey, Seema Rani Saraf, Jyotsana Shukla
Women dealing with gynecological issues like PCOS, PMS, dysmenorrhea, and menopause often face more than just physical discomfort—many also experience psychological distress such as anxiety, mood swings, and low self-esteem. While conventional treatments mostly focus on managing physical symptoms, the emotional impact often goes unaddressed. This study explores how individualized homoeopathic treatment can help reduce psychological distress in such cases. A total of 60 women between the ages of 12 and 45 participated in the study. Thirty of them received homoeopathic treatment, while the other thirty did not. Over the course of a few months, their well-being was evaluated using the WHOQOL-BREF questionnaire, which measures physical, psychological, social, and environmental quality of life. Remedies like Pulsatilla, Natrum Muriaticum, Ignatia, and Sepia were prescribed based on each woman’s unique symptom pattern. The results were promising—most of the women who received homoeopathic care showed noticeable improvements in their emotional well- being, mood stability, and overall quality of life. Many also experienced better menstrual regulation and stress relief. In contrast, the group that didn’t receive treatment showed minimal improvement. These findings suggest that homoeopathy may offer a gentle, holistic way to support women’s emotional and psychological health in the context of gynecological problems. However, more large-scale studies are needed to confirm these benefits over the long term.