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Metallic Nanocarriers in the Delivery of Phytomedicines
(Cambridge Scholars Publishing, 2023) Tarique Mahmood Ansari; Laxmi Devi, Poonam Kushwaha, Ashish Kumar
Phytomedicines derived from plants have a wide range of pharmacological applications in a variety of diseases. One of the most important advantages of phytoconstituents is their low toxicity and adverse effects. However, their therapeutic efficacy is hampered by low solubility, permeability, and specificity in the target region. As a result, novel drug delivery systems are being developed employing a variety of nanoformulation methodologies to overcome these limitations and provide consistent drug delivery at the targeting location in the optimal concentration as well as increased therapeutic efficacy. Novel drug delivery systems are one example of such approaches (NDDS). In comparison to alternative options, using herbal formulations for NDDS is more advantageous. The utilization of inorganic nanoparticles of plant extract is an important idea for the herbal formulations. These are used to achieve the targeted administration of the formulation, which influences the location and enhances its bioavailability. The constituents and extracts used in natural formulations demonstrate sustained release, enhanced stability, increased therapeutic efficacy, and toxicity prevention due to such novel drug delivery systems. The fundamental motivation for developing alternative drug delivery systems is