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    Liposomes: History, Properties, and Applications
    (Nova Science Publishers, Inc, 2024) Shivangi Sharma, Anas Islam, Mohd Muazzam Khan, Usama Ahmad
    The use of liposomes in nanotechnology has become more widespread in recent years. Liposomes are self-assembled particles having a water chamber that is surrounded by a lipid bilayer. This chapter has covered the liposomes in great detail, including how and where they were created, a broad description of their structure, and what distinct types of lipids they are composed of. Depending on their size, liposomes can be classified into several distinct varieties, such as enormous liposomes, multilamellar liposomes, and unilamellar liposomes. Depending on the context, different liposomes can be produced using various preparation techniques. In this chapter, we have also learned about the several fields in which liposomes have been extensively employed for the treatment of various diseases, biotechnology research, cosmetic items, nutraceuticals, and food. To increase the stability of the core, liposomes are important in the encapsulation of a variety of bioactive compounds (BACs), including functional food additives. In this chapter, we have also discussed the future perspective and scope where liposome technology can be exploited, the different fields in which liposome nanotechnology can be a boon, and the revolution it can make in pharmaceuticals.
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    Perspective Chapter: Nose-to-Brain Drug Delivery through Liposomes - Recent Applications
    (IntechOpen, 2023) Abdul Hafeez; Shazia Afzal Usmani
    Diseases related to the brain are causing a huge problem worldwide. Different drug formulations are available for the management of brain-related disorders, but due to less drug availability for the brain and non-specificity, it becomes difficult to completely cure life-threatening brain disorders. The blood-brain barrier (BBB) restricts the entry of drug molecules/drug-loaded carriers because of the presence of various efflux transporters and drug inactivating enzymes. Researchers have identified an intranasal route for direct delivery to the brain, bypassing BBB. Nanotechnology-enabled lipid-based drug carrier systems have shown potential for the management of brain diseases through nose-to-brain delivery. Liposomes are the most extensively investigated carrier systems because of biocompatibility, controlled release characteristics, easy surface modification, and biodegradability. This chapter highlights the important aspects of nose-to-brain delivery and strategies for enhancing the availability of drugs through liposomes in the management of different brain-related diseases.