Faculty Publications

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Scholarly Publications by Integral Academia

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    A Futuristic Approach on the Multifunctionality of Nanomaterials: Relevance of Nanoparticles
    (IGI Gobal, 2024) Faria Fatima
    The realm of analytical chemistry has been invigorated by the advent of multifunctional nanoparticles. Nanomaterials, with their distinct properties stemming from quantum effects and high surface-to-volume ratios, are poised to reshape industries ranging from electronics to medicine and environmental sustainability as they deliver unprecedented performance by integrating semiconducting, plasmonic, and piezoelectronic properties. Furthermore, multifunctional nano species play a pivotal role in personalized medicine and targeted therapies. Magnetic nanoparticles respond to magnetic fields and are employed in hyperthermia therapy and targeted drug delivery. The utilization of nanostructures for promoting environmental sustainability is highly commendable. They have the remarkable ability to pinpoint pollutants and their degradation. Therefore, as the research progresses, there are transformative breakthroughs to harness the multifunctionality of nanomaterials across scientific domains, driving society towards a future characterized by technological marvels and sustainable progress.
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    Hybrid Nanomaterials: A Sustainable Tool to Detect Environmental Problems
    (IGI Gobal, 2024) Faria Fatima
    Hybrid nanomaterials, a novel class formed by integrating organic and inorganic components at the nanoscale, have gained attention in nanotechnology and materials science. This synergy creates structures with enhanced functionalities. In environmental detection, they play a crucial role due to their sustainable and cutting-edge attributes. This chapter examines their pivotal role in addressing environmental issues, leveraging diverse nanomaterial properties. With tunable properties, high surface area, and sensitivity, hybrid nanomaterials are ideal for sensing environmental parameters. Their sustainability aligns with the global push for eco-friendly solutions, extending to applications in renewable energy and waste reduction. The chapter explores synthesis methods, sensor design intricacies, and applications, highlighting their potential to revolutionize environmental monitoring and contribute to a sustainable future through advancements in detection technologies.
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    Exploring the Transformative Potential of Hybrid Nanoparticles in Biomedical Applications: Relevance of Hybrid Nanoparticles
    (IGI Gobal, 2024) Faria Fatima
    Hybrid nanoparticles are nanoscale particles that are composed by interaction between the different components, resulting in enhanced properties that can be harnessed for wide range of application across fields like medicine, electronics energy, and more. These nanoparticles are typically in the size range from 1-100 nanometers, which is advantageous. Because at this scale, they often exhibit novel behavior due to their quantum and surface effects. The choice of material and the way they are combined can be tailored to achieve specific goals. For example, in biomedical applications, hybrid nanoparticles can be engineered to have specific targeting abilities such as targeted drug delivery, theranostics, gene therapy, phototherapy, tissue regeneration, vaccines, antibacterial, biomolecules detection, imaging probes, tissue engineering, biosensing, and cancer treatment. They have enhanced qualities with increased target specificity and sensitivity, extended circulation times, and resistance to biological barriers.
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    Exploiting the Bioprospecting Potential of Nanoparticles with Micro-organisms
    (CRC Press, 2024) Faria Fatima
    Biosynthesis of nanoparticles (NPs) using micro-organisms has emerged as a rapidly developing research area in nanotechnology with various biological entities constantly being used in NPs synthesis, forming an impute alternative to conventional chemical and physical methods. Micro-organisms such as bacteria, cyanobacteria, actinomycetes, yeast and fungi are known to produce inorganic nanoparticles such as gold, silver, silicon, iron, gypsum, titanium, zinc, manganese, lead etc. Metal capture, enzymatic reduction and capping are all steps in the formation of nanoparticles by microbes where metal ions are trapped on the surface or inside microbial cells before being reduced to nanoparticles in the presence of enzymes. Likewise with bacteria, the fungi are used to synthesize nanoparticles after being cultured on agar and then transferred to a liquid medium. The electrostatic binding of metallic ions to the negatively charged carboxylate groups in the enzyme present on the cell wall of mycelia causes intracellular synthesis. Nanoparticles’ most commonly reported modes of action are antimicrobial activity, ROS-induced cytotoxicity, genotoxicity, plant growth promotion, environmental remediation and so on. The controlled synthesis of nanoparticles via beneficial micro-organisms has been successfully validated which is to be directed by their size, shape, dose and concentration dependant.
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    Potent inflammatory biomarkers in insulin resistance
    (Elsevier Academic Press, 2024) Faria Fatima
    Diabetes has become an epidemic in the developed world. Insulin resistance is a crucial element in diabetes development, occurring 10–20 years before the illness manifests itself. Insulin resistance has been linked to persistent low-grade inflammation. This chapter will go over several types of insulin resistance as well as the involvement of inflammatory biomarkers in insulin resistance. We found that numerous cytokines, including IL-10, IL-6, IL-1, TLR4, TNF-alpha, and NF-B, are found to play crucial roles in the development of insulin resistance. Getting active, controlling weight, taking medicine, managing stress, striving for appropriate sleep, adopting a balanced diet, cutting back on sugar and simple carbs, and consuming fiber-rich foods like whole grains, vegetables, beans, and lentils are important measures to reduce insulin resistance. These adjustments might reduce insulin resistance and enhance blood sugar regulation.