Diabetes has become an epidemic in the developed world. Insulin resistance is a crucial element in diabetes development, occurring 10–20 years before the illness manifests itself. Insulin resistance has been linked to persistent low-grade inflammation. This chapter will go over several types of insulin resistance as well as the involvement of inflammatory biomarkers in insulin resistance. We found that numerous cytokines, including IL-10, IL-6, IL-1, TLR4, TNF-alpha, and NF-B, are found to play crucial roles in the development of insulin resistance. Getting active, controlling weight, taking medicine, managing stress, striving for appropriate sleep, adopting a balanced diet, cutting back on sugar and simple carbs, and consuming fiber-rich foods like whole grains, vegetables, beans, and lentils are important measures to reduce insulin resistance. These adjustments might reduce insulin resistance and enhance blood sugar regulation.
