Faculty Publications

Permanent URI for this communityhttp://192.168.24.11:4000/handle/123456789/7

Scholarly Publications by Integral Academia

Browse

Start date: 2016Subject: search.filters.subject.Chemistry

Search Results

Now showing 1 - 10 of 61
  • Thumbnail Image
    Item
    3D-printed polymer composites for electrochemical energy storage
    (Woodhead Publishing, 2026) Ekhlakh Veg, Tahmeena Khan
    Additive Manufacturing of Polymer Composites: Materials Processing, Structural Designs and Applications Edited by: Yasir Beeran Pottathara, Hanuma Reddy Tiyyagura, Kalim Deshmukh
  • Thumbnail Image
    Item
    Green-Synthesis of ZnO Nanostructures Using Aqueous Leaves Extract of Rosa Indica: Photocatalytic Under Solar Light Irradiation
    (Tashkent Institute of Chemical Technology, 2026) Suneel, Mohd Shabbirb, Qazi InamurRahman
    Recent studies have demonstrated a dramatic escalation in global water consumption, with an approximate 600% increase over the past century. Due to the expansion of textile, there is a release of synthetic organic dye effluents, which are contributing to the deterioration of water quality, rendering it unsuitable for potable use, posing significant threats to both human health and aquatic ecosystems. Notably, the textile sector alone utilizes approximately. 100,000 metric tons of dyes annually, with approximately 15% of these chromophonic compounds being inappropriately discharged into aquatic environments and surface water systems. Green- synthesised zinc oxide (ZnO) has emerged as a competitive photocatalyst due to its superior electron mobility.
  • Thumbnail Image
    Item
    Synthesis and Pharmacological Potential of Pyrimidine Derivatives in Neurodegenerative Diseases
    (Tashkent Institute of Chemical Technology, 2026) Vasundhara Yadav., Malik Nasibullah
    Pyrimidine derivatives represent a vital class of heterocyclic compounds with broad pharmacological applications, particularly in the treatment of neurodegenerative disorders such as Alzheimer's disease (AD) and Parkinson's disease (PD) [1]. These disorders are characterized by progressive neuronal degeneration, oxidative stress, and neurotransmitter imbalance [2]. This review systematically analyzes recent advances (2010-2025) in the synthesis and biological evaluation of pyrimidine-based compounds. Various synthetic methodologies, including cyclization, multicomponent reactions, and nucleophilic substitution, have been employed to generate structurally diverse derivatives [3]. Pharmacological studies demonstrate that these compounds exhibit significant acetylcholinesterase inhibition, antioxidant, anti-inflammatory, and neuroprotective activities [5], [6]. Structure-activity relationship (SAR) analysis indicates that substitution patterns on the pyrimidine ring critically influence biological activity [4]. Overall, pyrimidine scaffolds offer promising potential for the development of multi-target-directed ligands for neurodegenerative diseases.
  • Thumbnail Image
    Item
    Advancements in Powertrain Architectures and Energy Management Strategies for Electric and Hybrid Vehicles: A Mechanical Engineering Perspective
    (İstanbul, Türkiye, 2025) Mohd Saad Saleem, Saimah Khan
    This chapter provides a comprehensive examination of the revolutionary developments in electric and hybrid vehicle powertrain technologies from 2020 to 2025. The analysis reveals that series-parallel hybrid systems have achieved market dominance with 89% growth in 2024, while advanced energy management strategies demonstrate potential for 20-35% overall system efficiency improvements. The integration of emerging technologies such as solid-state batteries with 750-mile range potential and multi-phase motor architectures achieving 10% efficiency gains represents a paradigm shift toward sustainable transportation solutions. From a mechanical engineering perspective, the field faces critical challenges in thermal management system design, vibration control for in-wheel motor applications, and the integration of advanced power electronics with traditional mechanical systems.
  • Thumbnail Image
    Item
    A Computational Study of Chalcone Derived Cu(II) and Zn (II) Complexes
    (Book Rivers, 2026) Supreet, Tahmeena Khan, Mohammad Imran Ahmad
    The simplicity of chalcone chemistry, coupled with the ease of structural modification and straightforward synthesis, has made them a focal point for medicinal chemists exploring a wide range of biological applications. Chalcone derivatives, renowned for their diverse biological activities, have gained significant attention in recent years. In this chapter, we employed computational methods to investigate the physicochemical properties of Cu(II) and Zn(II) complexes derived from various chalcone derivatives which lead to the identification of drug likeness. Computational predictions offer a powerful tool for accelerating drug discovery. By predicting molecular structure, properties, and potential side effects, these techniques can help identify promising lead compounds and optimize their design. Additionally, computational methods can aid in the identification of disease-specific targets, streamlining the development process. Careful consideration of ADMET properties, pharmacokinetics, metabolism, and safety profiles is essential to ensure the clinical viability of these compounds. The results obtained provide insights into the factors influencing the stability, reactivity, and potential biological activity of these metal complexes.
  • Thumbnail Image
    Item
    Revolutionizing the Oil and Gas Industry through Nanotechnology
    (Proceedings of the International Conference on the topic “Innovative approaches to localization, 2023) Sabeeha Jabeen, Shashi Bala, Abdul Rahman Khan, Tahmeena Khan
    Nanotechnology has the potential to change the technological landscape of the oil and gas industry. Current research is exploring the use of nanotechnology in different aspects related to the oil and gas industry. This review summarizes the research advances in the field of drilling and processing and, the development/improvement of oil recovery using nanotechnology. Such information can help researchers understand current research and expand the applications of existing nanomaterials and elucidating the special properties of nanomaterials will continue to increase the use of nanomaterials in the oil petroleum and natural gas sectors.
  • Thumbnail Image
    Item
    CuO NANOPARTCLES AND THEIR ANTIBACTERIAL ACTIVITY EVALUATION
    (Zenodo, 2024) Sabeeha Jabeen, Ekhlakh Veg, Shashi Bala, Seema Joshi, Tahmeena Khan
    The development of antibiotic resistance is one of the most pressing problems in global healthcare. Microbial resistance to antibiotics might be combatted by the use metal-oxide-based nanoparticles (NPs). Many studies have shown that Copper oxide nanoparticles (CuO NPs) have potent antibacterial activity against different Gram-positive and Gram-negative bacteria. This review summarizes some recent studies to investigate the antibacterial activity of the CuO NPs fabricated from different strategies, particularly green synthesis which has emerged as an environment-friendly approach for the fabrication of NPs.
  • Thumbnail Image
    Item
    Nanoconjugation of Schiff Bases for Biological Activity Enhancement
    (Zenodo, 2024) Ekhlakh Veg, Sabeeha Jabeen, Seema Joshi, Tahmeena Khan
    Schiff bases form metal chelates which show good antimicrobial, anticancer properties etc. Due to poor solubility, poor bioavailability, researchers now conjugated these Schiff bases to nanoparticles which enhance the solubility and bioavailability for better results. This paper reports the nanocojugation of Schiff bases and their diverse biological activities. Keywords: Schiff bases, Antimicrobial, anticancer, nanoparticles etc.
  • Thumbnail Image
    Item
    PER- AND POLYFLUOROALKYL SUBSTANCES (PFAS) IN COSMETICS: OCCURRENCE, EXPOSURE PATHWAYS, HEALTH CONCERNS AND EMERGING REGULATORY RESPONSES
    (Liberty Academic Publishers, 2025) Saimah Khan
    Per- and polyfluoroalkyl substances (PFAS) are a large class of synthetic fluorinated chemicals increasingly recognized as persistent environmental and human contaminants (EPA, 2023; Peaslee et al., 2021). PFAS are intentionally added to many cosmetic and personal care products to enhance spreadability, water resistance, film formation, and long-lasting performance, and may also enter formulations unintentionally as impurities or degradation products of precursor ingredients (FDA, 2025; ToxStrategies, 2025). Recent analytical surveys report that a substantial proportion of foundations, mascaras, lipsticks, and other colour cosmetics sold in North America and Europe contain high levels of fluorine, suggesting widespread PFAS use (Peaslee et al., 2021; University of Notre Dame, 2024). While cosmetics are not the dominant source of aggregate PFAS exposure, their direct, frequent application to skin, lips, and peri-ocular areas raises concern, particularly for long-lasting and waterproof products marketed for daily use (Exponent, 2026; Wigle et al., 2025). Multiple epidemiological and toxicological studies link certain well-studied PFAS (for example, PFOA and PFOS) to kidney and testicular cancers, immune suppression, endocrine disruption, dyslipidaemia, and developmental toxicity, although cosmetic-specific risk assessments remain limited and uncertain (WHO, 2022; ECHA, 2023).
  • Thumbnail Image
    Item
    Evaluating the Marketing Strategy of BYD Electric Vehicles in India
    (Book Rivers, 2026) Ayush Maurya, Firoz Husain