Faculty Publications

Permanent URI for this communityhttp://192.168.24.11:4000/handle/123456789/7

Scholarly Publications by Integral Academia

Browse

Start date: 2021Subject: search.filters.subject.Chemistry

Search Results

Now showing 1 - 10 of 43
  • Thumbnail Image
    Item
    Formulation and Evaluation of Telmisartan Sustained-Release Tablets
    (Book Rivers, 2026) Suraj Kumar, Mohd Arsh Khan, Sabahat Yasmeen Sheikh, Firoz Hassan
    The study concentrates on developing and accessing extended-release floating tablets that include Telmisartan, a medication typically prescribed for treating hypertension. Different polymer ratios were utilized in creating various formulations through direct compression methods to regulate the release of the drug. Quality assurance measures encompassed testing pre-compression and post-compression parameters such as hardness, friability, and drug content. One of the formulations, F5, stood out for its optimal drug release, reaching an impressive 97% over 20 hours. The stability studies performed on F5 revealed no notable alterations within three months under ICH conditions, thus verifying the formulation's strength. The results suggest that the improved formulation can improve patient adherence and maximize drug absorption, offering promising advantages in the effective treatment of hypertension through prolonged medication effectiveness.
  • Thumbnail Image
    Item
    Isatin and its Analogues as Promising Biological Agents
    (Book Rivers, 2026) Mohd Arsh Khan, Ziaul Husain, Sabahat Yameen Sheikh, Firoj Hassan
    The synthesis of isatin derivatives hold significant potential in various fields, particularly in pharmaceuticals and materials science. The synthesis of isatin derivatives represents a significant area of research with promising implications across various fields including medicinal chemistry, materials science, and organic synthesis. Through this, we have delved into the intricate methodologies and strategies employed in the synthesis of these compounds, aiming to provide a comprehensive overview of the advancements, challenges, and future prospects in this domain. Our investigation began with an exploration of the significance of isatin derivatives, highlighting their diverse biological activities and potential therapeutic applications. Structure-activity relationship (SAR) analysis was conducted to correlate the chemical modifications with observed biological activities, providing a foundation for future optimization and development. In conclusion, this chapter contributes to the growing body of knowledge on isatin chemistry, offering new insights into the synthesis, and potential applications. The findings underscore the importance of tailored chemical modifications in enhancing the properties and functionalities of isatin-based compounds.
  • Thumbnail Image
    Item
    AZOLE DERIVATIVES AND THEIR BIOLOGICAL ACTIVITIES
    (Book Rivers, 2026) Vaishnavi Dubey, Mohd Arsh Khan, Neda Fatima, Sabahat Yasmeen Sheikh, Firoj Hassan
    Azoles, a significant category of nitrogen-containing heterocycles, have attracted considerable interest in medicinal chemistry due to their structural flexibility, capacity to form hydrogen bonds, and diverse biological effects. This chapter delves deeply into azole derivatives, highlighting their synthesis and their importance in pharmacology. Azoles, such as imidazole and benzimidazole derivatives, are renowned for their significant contribution to the advancement of antifungal, anticancer, and antimicrobial medications. The chapter explores various synthetic methods, including Williamson etherification and regioselective nucleophilic ring-opening reactions, used to produce coumarin-based azole derivatives. These derivatives exhibit remarkable therapeutic properties due to their distinct structural features and interactions with biological targets. Furthermore, the crucial role of nitrogen heterocycles in FDA-approved medications is highlighted, underscoring their extensive use in the development and manufacture of drugs. This chapter highlights the vital role of nitrogen-containing heterocycles in contemporary pharmacology and their ability to tackle a wide range of medical issues through showcasing examples of clinically approved drugs and recent breakthroughs.
  • Thumbnail Image
    Item
    Trends In Medicinal and Environmental Science: An Introduction
    (978-93-6884-737-3, 2026) Iqbal Azad, Jamal Akhtar Ansari, Malik Nasibullah, Abdul Rahman Khan
  • Thumbnail Image
    Item
    Bridging Disciplines with a Particular Emphasis on Chemistry
    (Bentham Science, 2026) Kulsum Hashmi, Tahmeena Khan, Manisha Singh, Saman Raza, Seema Joshi, Abdul Rahman Khan
    Abstract: Interdisciplinary education has gained considerable attention in higher education institutions. The focus of interdisciplinary education is to integrate diverse perspectives and methods to solve complex real-life challenges. By integrating insights, methods, and knowledge from multiple academic fields, interdisciplinary teaching provides students with a comprehensive and integrated learning experience. Interdisciplinary learning is a highly complex area in modern education that, despite its importance, has not been sufficiently theorized or researched. The conventional teaching model limits students' development of comprehensive qualities and fails to fully engage students' interests. Several challenges are also presented by interdisciplinary education, despite its potential benefits. Integrating multiple disciplinary perspectives into a cohesive curriculum is one of the main obstacles. Faculty members are required to collaborate across departments and create innovative pedagogical approaches to bridge the gaps between disciplines. Integrated interdisciplinary teaching models have gradually emerged as effective strategies to address these challenges as a result of the continuous evolution of modern educational concepts. This paper investigates the aids and methods of interdisciplinary teaching, including project-based learning, problem-based learning, competency-based learning, and thematic learning. This study aims to explore the effects of interdisciplinary science learning on sustainability-focused education, with a particular emphasis on chemistry's inherent relationship to other disciplines. The integration of sustainable development concerns in teaching presents a productive opportunity as well as a challenge for chemistry education to strengthen its societal dimensions.
  • Thumbnail Image
    Item
    Bridging Disciplines: Interdisciplinary Approaches for Transforming Education
    (Bentham Science Publishers Pte. Ltd., 2026) Tahmeena Khan, Manisha Singh, Saman Raza
    In a world that is ever-changing and increasingly complex, a field such as education, which encompasses various disciplines, must work to prepare students to understand the connections between this complex world and to meet the uncertain demands of the future, as well as the pressing issues of the present. There is no doubt that traditional discipline-specific teaching methods are the foundation of the education system, but they are unable to meet the changing demands of today's education. There is a need for an approach that fosters connections between various disciplines and equips students with adaptable abilities, integrative thinking, and a collaborative mindset, essential for addressing today's world and its complexities. One such approach that may fulfil this need is addressed in this book titled " Bridging Disciplines: Interdisciplinary Approaches for Transforming Education." The book is a compilation of 14 chapters from contributions by different experts in their respective areas and therefore offers a rich account of insights, new frontiers, and interdisciplinarity across disciplines. Each chapter is constructed to be self-contained, allowing readers to dive in and out as their understanding permits. The book begins with an introduction to interdisciplinarity in education, where the chapter presents various related concepts, including interdisciplinary, multidisciplinary, and bridging disciplines, to enable readers to achieve a clear conceptual understanding upon completing this chapter. The second chapter, Bridging the Barrier Between Science and Arts, aims to reduce the gap between the two major categories of disciplines, viz., science and arts. The third chapter discusses various pedagogical strategies for Interdisciplinary Learning in a general domain. The subsequent chapters cover a broad spectrum of topics, written in a way that each chapter draws upon insights from various fields, including the STEAM paradigm, Commerce, Social Studies, Languages, Biological Science, Chemical Science, Mathematics, Environmental Science, and Architectural Studies. The last two chapters provide insight into creativity and AI tools in interdisciplinary research. The revolutionary potential of interdisciplinary approaches in education is explored in this book, which advocates for instructional models that break down silos, foster holistic understanding, and stimulate creativity by integrating multiple fields of knowledge. All the chapters are presented herein with the objective of rethinking curriculum, pedagogy, and learning methodologies. We aim to provide a comprehensive account of insights to the major stakeholders in the field of education, including educators, researchers, policymakers, and students, while promoting interdisciplinarity. Our vision for this book is to empower stakeholders with an education that is both meaningful and skilful, capable of standing up to global competition. This book would be helpful for students, teachers, researchers, and academicians who seek to integrate across different disciplines. We anticipate that educators, researchers, policymakers, and students will find inspiration and practical guidance within these pages. As we go towards more inclusive, adaptable, and future-oriented educational settings, may this book function as both a resource and a stimulus for continuous experimentation and discourse. As the editors of this book, we would like to thank the contributing authors for their time and expertise. We also want to thank the readers whose curiosity and commitment to advancing education through technology drive our ongoing investigation of this fascinating intersection.
  • Thumbnail Image
    Item
    Frontiers in Pharmaceutical, Material, and Environmental Sciences: Innovative Approaches and Applications
    (Book Rivers, 2026) Tahmeena Khan, Qazi Inamur Rahman, Nafees Ahmad, Shahla Tanveer
    This book brings together a collection of research studies that delve into the fields of pharmaceutical science, materials science, and environmental science. The chapters within this volume highlight innovative methods and significant discoveries in these areas. The research presented here explores the development of advanced drug delivery systems, the therapeutic potential of natural products, the removal of environmental pollutants, and the optimization of material properties. By combining experimental techniques with computational modeling, the authors have gained deeper insights into the underlying mechanisms of these processes. We hope this book will serve as a valuable resource for researchers, academics, and industry professionals in these fields. The knowledge and insights provided here will contribute to the advancement of scientific research and the development of sustainable solutions for global challenges.
  • Thumbnail Image
    Item
    Perspectives of Medicinal, Material and Environmental Chemistry
    (Book Rivers, 2026) Saimah Khan, Naseem Ahmad, Firoz Hassan
  • Thumbnail Image
    Item
    Conclusion and Future Directions in Anticorrosive MOF-Based Coatings
    (CRC Press, 2026) Farhat Aisha Ansari, Humira Assad
  • Thumbnail Image
    Item
    Synthesis, Characterization, Pharmacokinetics & Admet Studies of Schiff Bases
    (Book Rivers, 2026) Ayesha Anwer, Mohammad Amir, Umme Habiba Malik, Malik Nasibullah
    Isatin (1H-indole-2,3-dione) and its derivatives are heterocyclic molecule that can be employed as precursor for the synthesis of medicinally relevant molecules. Interestingly, the formation of imine (CN) or azomethine group through the reactivity among primary amine and carbonyl compounds could be easily identified by FT-IR analysis owing to the stretching of the imine system found at 1640 per cm, as noted in the preceding work. Schiff bases are versatile ligands that are useful in asymmetric reactions to prepare chiral catalysts and also in symmetric reactions to prepare achiral compounds. They are widely used for industrial purposes and also exhibit a broad range of biological activities. The German chemist Hugo Schiff, in 1864, first described the product as the condensation of primary amines with carbonyl compounds. Schiff bases have a wide range of biological properties, such as anti-microbial, anti-viral, and anti-cancer.