Faculty Publications

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Scholarly Publications by Integral Academia

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    GC-MS Profiling and Antioxidant Activity of Musa paradisiaca L. Peels Fractions
    (Book Rivers, 2026) Azeem Fatima, Mohd Arsh Khan, Shahzadi Bano, Abdul Rahman Khan, Jamal Akhtar Ansari
    This study investigates the phytochemical composition and antioxidant activity of Musa paradisiaca L. (banana) peel extracts. Using GC-MS profiling, various chemical compounds within the peels were identified, including multiple phytochemicals with potential medicinal properties. Extraction and fractionation were performed with solvents of varying polarities, and antioxidant activity was measured using DPPH radical scavenging assays. The findings reveal a significant presence of compounds such as alkaloids, flavonoids, and reducing sugars, with high antioxidant potential observed particularly in chloroform and ethyl acetate fractions. This study highlights the potential of Musa paradisiaca peels as a source of bioactive compounds for pharmaceutical and nutraceutical applications, suggesting further research on their therapeutic benefits.
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    Phytochemical Innovations and their Therapeutic Role in Neurodegenerative Disorders
    (Zenodo, 2026) Farhat Aisha Ansari, B. Ali Modu, Samar Mujeeb
    Neurodegenerative disorders such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and Huntington’s disease (HD) are progressive neurological conditions associated with cognitive decline, neuronal loss, and impaired quality of life. The increasing prevalence of these disorders and the limitations of existing therapeutic options have encouraged exploration of medicinal plants as alternative neuroprotective agents. The objective of this study is to examine current trends in medicinal plant research and evaluate their therapeutic relevance in neurodegenerative disorders. The methodology involved a narrative review and scientific evaluation of published literature focused on medicinal plants, phytochemicals, ethnopharmacological evidence, and molecular mechanisms associated with neuroprotection. Data from recent studies were analyzed to identify major bioactive compounds and their mechanisms of action. The findings indicate that medicinal plants and plant-derived compounds demonstrate significant neuroprotective activities through antioxidant, anti-inflammatory, anti-apoptotic, and signaling pathway modulation mechanisms. Bioactive constituents including flavonoids, polyphenols, alkaloids, and terpenoids have shown the ability to regulate oxidative stress, mitochondrial dysfunction, protein aggregation, and neuroinflammation. Several medicinal plants including Bacopa monnieri, Ginkgo biloba, Panax ginseng, and Centella asiatica have exhibited promising therapeutic outcomes in experimental and preclinical studies. In conclusion, medicinal plant research offers a promising direction for developing safer and multi-target therapeutic strategies for neurodegenerative disorders. Integration of traditional medicinal knowledge with modern pharmacological approaches may support future advancements in neuroprotective drug discovery.