Faculty Publications

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Scholarly Publications by Integral Academia

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    Antitubercular Potential of Bioactive Phytoconstituents from Andrographis Paniculata: Targeting DprE1 of Mycobacterium Tuberculosis
    (Zenodo, 2026) Samar Mujeeb, Farhat Aisha Ansari
    Tuberculosis (TB) remains one of the leading infectious diseases worldwide, and the emergence of multidrug-resistant strains has intensified the need for novel therapeutic agents. Medicinal plants continue to provide structurally diverse bioactive molecules with significant drug discovery potential. Andrographis paniculata (Kalmegh) is widely recognized for its antimicrobial and immunomodulatory activities and may represent a promising source of antitubercular lead compounds.
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    Antimicrobial, Antioxidant and Anticancer Potential of Andrographis Paniculata: Phytochemical Insights and Biomedical Implications
    (Book Rivers, 2026) Hina Khatoon, Mohammad Haneef, Salman Akhtar
    Oxidative stress and cancer continue to pose major challenges to global health, contributing significantly to illness and death worldwide. Growing concerns over the adverse effects of synthetic drugs have intensified interest in natural, plant-based remedies. This chapter presents an in-depth overview of the antioxidant and anticancer potential of Andrographis paniculata, commonly referred to as the "King of Bitters." It delves into the biochemical basis of oxidative stress, the therapeutic relevance of antioxidants, and the crucial role of natural compounds in cancer prevention and therapy. Additionally, the chapter discusses the phytochemical constituents, traditional applications, and pharmacological benefits of A. paniculata, particularly its anti-inflammatory, hepatoprotective, antidiarrheal, and anticancer effects. Emphasis is placed on the need for further targeted research to substantiate its clinical effectiveness and safety, underscoring its promise in the development of innovative therapeutic agents.