Faculty Publications
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Scholarly Publications by Integral Academia
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Item Neuropathology of Neurological Disorders(Springer Nature, 2024) Andleeb KhanNeuropathology delineates the examination of cells and tissues, to assimilate the structure and function of the neurological system as well as the diagnosis and pathology of diseases that impact the nervous system. It studies the effects of disease on the nervous system and can be used to diagnose and categorize particular neurological conditions. This comprises studies of the muscles, nerves, and ganglia (the peripheral nervous system), and the brain and spinal cord (the central nervous system). A wide array of techniques such as immunohistochemistry, molecular biology, and light and electron microscopy are being used to observe neuropathological alterations in various neurological disorders. Neuropathology highlights the structural and functional observations of neurological diseases ranging from cellular to micro-anatomical constructs to identify the biomarkers that are responsible for the progression of the diseases. Several imaging technologies are also used which include CT scans and MRI to deeply examine the modifications in neurological disorders. The examination of several neurological disorders, such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and multiple sclerosis, rests severely on neuropathology. In this chapter, we will discuss about the neuropathology of several neurological disorders.Item Mitochondrial Dysfunction and Its Role in Neurological Disorders(Springer Nature, 2024) Andleeb KhanMitochondria, pivotal cell organelles recognized for their paramount role in cellular energy production, play a crucial part in neurological disorders such as Parkinson’s disease (PD), Alzheimer’s disease (AD), and multiple sclerosis when their functionality falters. Among the repercussions of mitochondrial dysfunction, neuroinflammation emerges as a prominent concern, eliciting an upsurge in the generation of reactive oxygen species (ROS). The deleterious effects of these ROS on nerve cells induce a cascade toward neurodegeneration. This chapter comprehensively delves into the adverse implications of mitochondrial dysfunction on the advancement of diverse neurological ailments, with particular emphasis on the pivotal role of neuroinflammation.Item Weed Bio-Control Agents(CRC Press, 2023) Uzma AfaqItem Various Metabolites and Bioactive Compounds from Fruits, and Their Use in Nanoparticles Synthesis and Applications(Springer Nature Singapore Pte Ltd., 2023) Siddiqui, Arshi; Dixit, Pragyesh; Moid, Hira; Afaq, UzmaCommercially valuable bioactive compounds find a vast range of applications in the medical, pharmaceutical, cosmetic, agriculture and food industry. Nanotechnology is a promising and rapidly emerging field of science. Due to their vast range of applications in the medical, pharmaceutical, cosmetic, agriculture and food industry, bioactive compounds (e.g., flavonoids, phenolic acids, alkaloids, and carotenoids) are commercially valuable goods. Controlled elicitation is one of the promising techniques for enhancing the production of bioactive chemicals in plants. Nanoparticles (NPs) are novel elicitors of bioactive chemicals in plants and could impact the plant’s secondary metabolism. The biological production of nanoparticles is becoming more widely recognized as a rapid, environmentally benign, and easy to scale up method. Metallic nanoparticles synthesized from microorganisms and plant extracts are stable and monodispersed when synthesis parameters including pH, temperature, incubation time, and mixing ratio are well controlled. The goal of this chapter is to outline fruit extract NPs synthesis and their various applications.Item Application of Molecular Markers in Revealing Genetic Stability Among In Vitro Regenerants of Different Valeriana Species- a Pharmaceutically Valued Plant(Bentham Science Publishers, 2023) Saeed, Taiba; Ganie, Irfan Bashir; Tahseen, Sabaha; Wasi, Adla; Ahmad, Zishan; Shahzad, AnwarItem ROLE OF FUNGI IN BIOREMEDIATION OF POLLUTANTS(Blue Duck Publications, 2023) Khatoon, JahanarahItem Wild Edible Medicinal and Aromatic Plants in Ancient Traditions(CRC PRESS, 2023) Irfan Ahmad Ansari; Shireen Fatima; Prakriti Mishra; Mahima VermaMedicinal and aromatic plants are beneficial to human health. Plant-derived molecules possess biological activities that can be used to prevent many infectious diseases and metabolic disorders. Ethnobotany and Ethnopharmacology of Medicinal and Aromatic Plants summarizes techniques and methods used to study the biological activities of plant-derived extracts and compounds to study ethnobotanical and ethnopharmacological features of medicinal and aromatic plants.Item Biomedical Waste: Impact on Environment and Its Management in Health Care Facilities(Springer, 2023) Singh, Sangeeta; Sonkar, Gyanendra Kumar; Sonkar, Satyendra KumarWaste of any origin, if not properly disposed, possess a significant threat to the environment. Biomedical waste is a potential health hazard generated from institutions and laboratories providing health care facilities which includes all sorts of pathological, pharmacological, gentoxic, chemical, and radioactive wastes. About 20% of waste generated during patient care is hazardous and carries various health risks to hospital staff, patients, attendants, and the general population. Proper segregation and disposal of biomedical waste is the need of the hour as it will prevent contamination of groundwater sources that affect the health of humans and animals. Proper packaging and labelling of waste prevent the spread of infection through humans and animals. Biomedical waste is the source of water contamination and, if not rendered harmless before it is buried in land or disposed of in the water. Biomedical waste contaminates air if not segregated or incinerated properly, resulting in highly hazardous airborne particles of contagious diseases. The diagnostic laboratories using radioactive substances are potential pollutants of landfills and the atmosphere. The spread of air pollutants over huge areas of inhabited land has the potential to trigger several illnesses. Hence, there should be the management of biomedical waste at each level (i.e., places of its generation, collection, storage, transportation, treatment, and disposal). The stakeholders, including health care sector, state pollution control board, and the municipal bodies, should work together to make the place safe for living with a neat and clean environment.Item Introduction to Agricultural Biochemistry(Book Rivers, 2022) Faria Fatima; Uzma AfaqItem IMMUNOPATHOLOGY, DIAGNOSIS, AND TREATMENT OF HPV-INDUCED MALIGNANCIES(Academic Press, 2022) Khare, Prashant ed.; Jain, Ashish ed.; Ansari, Irfan Ahmad
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