Antitubercular Potential of Bioactive Phytoconstituents from Andrographis Paniculata: Targeting DprE1 of Mycobacterium Tuberculosis
Date
2026
Journal Title
Journal ISSN
Volume Title
Publisher
Zenodo
Abstract
Tuberculosis (TB) remains one of the leading infectious diseases worldwide, and the emergence of multidrug-resistant strains has intensified the need for novel therapeutic agents. Medicinal plants continue to provide structurally diverse bioactive molecules with significant drug discovery potential. Andrographis paniculata (Kalmegh) is widely recognized for its antimicrobial and immunomodulatory activities and may represent a promising source of antitubercular lead compounds.
Description
Published June 18, 2026
PROCEEDINGS OF UZBEKISTAN–CHINA INTERNATIONAL SYMPOSIUM ON "CURRENT ISSUES IN THE CULTIVATION AND UTILIZATION OF MEDICINAL PLANTS"
Authors/Creators
Tashkent Chemical-Technological Institute (Hosting institution)
Keywords
Andrographis paniculata, Tuberculosis, DprE1, Molecular Docking, Molecular Dynamics Simulation, Drug Discovery