Neuroprotective Effects of Green Tea Extracts

Abstract

Deficits in cognition and movement are caused by neurodegeneration, which is a gradual deterioration in the composition and capabilities of nerve cells. Oxidative damage, inflammation, misfolded proteins, and heredity are among the contributing factors. Examples of diseases like these are Parkinson’s and Alzheimer’s. Potential neuroprotection against these processes is provided by green tea extracts. The Camellia sinensis plant yields green tea, which has drawn a lot of interest due to its abundance of bioactive substances, especially catechins. The chapter explores the expanding corpus of scientific literature, elucidating the several methods by which green tea extracts elicit their neuroprotective properties. The capacity of green tea extracts to counteract inflammation and oxidative stress—two important variables in neurodegenerative illnesses like Alzheimer’s and Parkinson’s—explains their neuroprotective qualities. These extracts show an amazing ability to scavenge free radicals, minimizing damage to neurons and improving mental performance. Furthermore, they moderate the expression of genes linked to neuroinflammation, reducing inflammatory reactions in the brain. This chapter also explores the function of green tea catechins in maintaining neuronal plasticity and stimulating the development of new neurons. These substances have promise in mitigating the consequences of age-related cognitive decline and neurological diseases by improving synaptic connection and promoting neurogenesis. A comprehensive review of several in vitro and in vivo investigations, clinical trials, and animal models highlights the strong evidence that green tea extracts have neuroprotective properties. With optimism for the management and prevention of neurodegenerative diseases, readers will obtain important insights into green tea’s potential as a readily available, natural neuroprotective agent.