Jamal Akhtar Ansari, Kashaf, Ayushi, Nasreen G. Ansari, Shahzadi Bano, Abdul Rahman Khan, Snober S Mir, Anam Saleem, Satyendra Kumar Singh2026-09-232026https://doi.org/10.5281/zenodo.21356314http://136.232.12.194:4000/handle/123456789/2212Conference THE UZBEKISTAN–CHINA INTERNATIONAL SYMPOSIUM ON "CURRENT ISSUES IN THE CULTIVATION AND UTILIZATION OF MEDICINAL PLANTS" , Tashkent, 18-19 June, 2026Medicinal plants remain an important source of bioactive compounds for the development of new therapeutics. In the present study, polarity-based fractions of Ricinus communis, Baliospermum montanum, Luffa acutangula, and Coriandrum sativum were evaluated for their antioxidant and antiproliferative activities against human breast cancer cell lines (MCF-7 and MDA-MB-231) and DPPH free radical scavenging assay. Several fractions exhibited significant, dose-dependent inhibition of cancer cell growth, with ethyl acetate and chloroform fractions showing the strongest activities and DPPH free radical inhibition. Chemical profiling by GC–MS/MS and LC–MS/MS tentatively identified a broad range of bioactive metabolites, including phenolics, terpenoids, and fatty acid derivatives. The findings suggest that these medicinal plants possess promising antioxidant and anticancer potential and may serve as valuable sources for the discovery of novel plant-derived therapeutic agents.en-USMedicinal PlantsAnticancer and Antioxidant ActivityBioactive MetabolitesGC–MS/MS and LC–MS/MS ProfilingArticle